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Synthetically lethal 翻译

WebDec 19, 2014 · These studies indicated that ~ 80% of S. cerevisiae genes are nonessential and the deletion of one gene is often buffered by other genes through a rich network of … http://www.ichacha.net/synthetic%20lethal.html

Development of synthetic lethality in cancer: molecular and …

WebAug 31, 2024 · Table insert, top synthetic lethal paralogs based on GI score. (D) Volcano plot of target-level GI scores in PC9 cells. FDR indicates the multiple hypothesis-adjusted p values from a two-tailed t test (Method details). Blue, synthetic lethal paralog GIs with GI < −0.5 and FDR < 0.1; red, buffering paralog GIs with GI > 0.25 and FDR < 0.1. Webadj. 1. 致命的;可致死的 causing or able to cause death. a lethal dose of poison. 毒药的致死剂量. a lethal weapon. 致命的武器. The closure of the factory dealt a lethal blow to the … teams black theme https://erinabeldds.com

synthetic lethality:バイオキーワード集|実験医学online:羊土社

Web肿瘤靶向治疗新方向---合成致死. 沉浮生信多年的老司机,带你起飞。. 个性化生信分析定制联系生信人. 1946年,Theodosius Dobzhansky发现并命名了“ 合成致死 ”效应。. 这个概念沉寂了51年后。. 1997年,在相关研究发现癌细胞携带有大量基因突变之后,福瑞德·哈金 ... WebThe PRMT5•MTA complex has recently emerged as a new synthetically lethal drug target for the treatment of MTAP-deleted cancers. Here, we report the discovery of development candidate MRTX1719. MRTX1719 is a potent and selective binder to the PRMT5•MTA complex and selectively inhibits PRMT5 activity in MTAP-deleted cells compared to MTAP … WebApr 19, 2024 · 2024年4月,Amgen,先声,Ryvu等分别在美国癌症研究协会(AACR)年会上,展示公司旗下蛋白精氨酸甲基转移酶5抑制剂的最新研发 ... spa at inn at the forks

The msc2 mutant is synthetically lethal with ire1 and

Category:synthetically replicate - 英中 – Linguee词典

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Synthetically lethal 翻译

synthetically replicate - 英中 – Linguee词典

Web例句仅用于帮助你翻译不同情境中的单词或表达式,我们并没有对例句进行筛选和验证,例句可能包含不适当的术语或观点。请为我们指出需要编辑或不应显示的例句。粗俗或口语化的译文通常用红色或橘黄色加以标记。 Web1.Lethal dwarfism syndromes are associated with brachycephaly or clover-leaf skull deformity rather than dolichocephaly. 致死性侏儒与短头畸形、三叶草头有关,而不是长头 …

Synthetically lethal 翻译

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Web英文翻译 手机版. synthetic lethal. "合成"英文翻译 compose; compound; synthetis ... "致死"英文翻译 causing death; lethal; deadl ... "合成致死染色體" 英文翻译 : synthetic lethal … WebThe most lethal complication is fulminating colitis . 最严重的致死性并发症是暴发性结肠炎。 It screens out lethal ultraviolet and x-rays from the sun . 它阻挡了来自太阳的致命的紫外线和X射线。 H2so4 is at least 100 times as lethal as so2 in guinea pigs . 在豚鼠中,硫酸致死性至少为二氧化硫致死性的一百倍。

WebMar 20, 2024 · NMTi eliminated MYC-deregulated tumors in vivo without overt toxicity, providing a new paradigm in which targeting a constitutive co-translational protein modification is synthetically lethal in MYC-deregulated cancers. One-sentence summary N -myristoyltransferase inhibition leads to post-transcriptional complex I failure and cell … Websynthetically的意思、解释及翻译:1. using processes or materials that are not found in nature: 2. in a way that seems false or not…。了解更多。

http://www.ichacha.net/synthetically.html Webn. = lethal gene. n. -ity 致死性,杀伤力;致死率。. adv. -ly. "synthetic" 中文翻译 : adj. 1.综合的;合成的; (橡胶等)人造的。. 2.代用的;摹拟的,假想的;虚构的;【语言学】综合 ( …

WebThe new england journal of medicine 1728 n engl j med 371;18 nejm.org october 30, 2014 to proteins by PARP enzymes) after PARP1 acti-vation.24,25 Collectively, these effects induce chromatin and ...

WebSep 3, 2024 · Synthetic lethality is a lethal phenomenon in which the occurrence of a single genetic event is tolerable for cell survival, whereas the co-occurrence of multiple genetic events results in cell death. The main obstacle for synthetic lethality lies in the tumor biology heterogeneity and complexity, the inadequate understanding of synthetic lethal … spa at hyatt regency huntington beachWeblethal翻译:致命的;极其危险的。了解更多。 spa atlas hardwarehttp://www.iciba.com/word?w=continually teams bleuWeb介绍了超重核合成的历史和现状 ,对现有的超重核合成的实验情况和理论模型做了评述 。 teams block external userWebfatal (adj.). 14世纪末,“由命运决定的”,也指“充满命运”,源自14世纪的古法语 fatal ,直接源自拉丁语 fatalis “由命运命定的,被命运或命运所属的;毁灭性的,致命的”,来自 fatum (参见fate(n.))。 原始意义已经过时;英语中“导致或伴随着死亡”的意义始于15世纪初。 teams blinking notificationsWebJan 1, 2011 · National Center for Biotechnology Information teams block screen captureWebsynthetic lethality(合成致死性).単独遺伝子欠損では細胞や個体に対する致死性を示さないのに,複数の遺伝子の欠損が共存すると致死性を発揮する現象.. 創薬標的の場合は2つの遺伝子変異で疾患との相関が強くなる創薬ターゲットを指す.一方の遺伝子 ... teams bluetooth speaker not working